Journal of perinatology : official journal of the California Perinatal Association
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Randomized Controlled Trial Comparative Study
A comparison of albumin-bolus therapy versus normal saline-bolus therapy for hypotension in neonates.
We compared responses to bolus infusion of 5% albumin (ALB) or normal saline (NS) for hypotension in neonates. ⋯ In hypotensive neonates, ALB results in a greater likelihood of achieving normotension and decreased subsequent use of vasopressors when compared to NS.
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To establish beginning evidence of clinical validity and reliability of the Neonatal Pain, Agitation and Sedation Scale (N-PASS) in neonates with prolonged pain postoperatively and during mechanical ventilation. ⋯ This research provides beginning evidence that the N-PASS is a valid and reliable tool for assessing pain/agitation and sedation in ventilated and/or postoperative infants 0 to 100 days of age, and 23 weeks gestation and above.
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Case Reports
Oral valganciclovir for symptomatic congenital cytomegalovirus infection in an extremely low birth weight infant.
Cytomegalovirus (CMV) infection is the most important congenital viral infection. Intravenous (i.v.) Ganciclovir (GCV) improved outcome in term infants with symptomatic congenital CMV infection. We present data on oral valganciclovir (VGCV) in an extremely low birth weight infant. ⋯ Clinical signs resolved and virus load decreased slowly during therapy. At discharge brain stem-evoked audiometry was normal. Oral treatment with VGCV in an extremely low birth weight preterm infant with congenital CMV infection resulted in adequate GCV plasma levels, reduced effectively the CMV viral load and was well tolerated without apparent adverse effects.
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The aim of this study was to measure pharyngeal pressures in preterm infants receiving high-flow nasal cannulae. ⋯ High-flow nasal cannulae at flow rates of 2 to 8 l min(-1) can lead to clinically significant elevations in pharyngeal pressure in preterm infants. Flow rate and weight but not mouth closure are important determinants of the pressure transmitted.
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Biography Historical Article
Avicenna (AD 980 to 1037) and the care of the newborn infant and breastfeeding.
A brief historical review of medicine during the fourth century Islamic civilization or eleventh century AD in Persia or Iran was undertaken with its focus on Avicenna. A physician-philosopher, named Ibn Sina or Avicenna (980 to 1037), followed and further expanded the tradition of western philosophy and medicine by Aristotle, Hippocrates and Galen. ⋯ This important textbook was extensively used in European medical schools for centuries after Avicenna's death. In the Canon of Medicine, a chapter is dedicated to the care of the newborn infant dealing with hygiene, breastfeeding and upbringing of the child.