Journal of perinatology : official journal of the California Perinatal Association
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Review Meta Analysis
Prophylactic antibiotics in the prevention of catheter-associated bloodstream bacterial infection in preterm neonates: a systematic review.
To evaluate the efficacy of prophylactic antibiotics in preventing infection associated with central venous catheters in preterm neonates. ⋯ Prophylactic vancomycin appeared to be effective in preventing catheter-related sepsis in preterm neonates. The potential risks, however, of the emergence of resistance because of prophylactic antibiotics, and their continued effectiveness, need further evaluation, before routine use can be recommended.