Journal of perinatology : official journal of the California Perinatal Association
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Randomized Controlled Trial
Effect of topical anesthesia and age on pain scores during retinopathy of prematurity screening.
The efficacy of topical anesthesia during retinopathy of prematurity (ROP) screening has been a controversial issue. To determine the efficacy of proparacaine eye drops (0.5%), we compared the Premature Infant Pain Profile (PIPP) scores in 40 preterm infants undergoing ROP screening. ⋯ Proparacaine eye drops offer significant relief of pain that is apparently short lived. Significantly lower PIPP scores at second ROP examinations suggested that infants of older GA may have a greater ability to tolerate ROP screening. We recommend the use of proparacaine eye drops for the short term, immediate relief of pain during ROP screening in preterm infants of lesser GA.
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To characterize the risk factors for late-onset circulatory collapse (LCC) in preterm infants responsive to corticosteroid therapy and evaluate the long-term neurological prognosis. ⋯ LCC is associated with poor neurodevelopmental outcomes. Prevention of LCC can lead to improved neurological prognoses.