Journal of perinatology : official journal of the California Perinatal Association
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Multicenter Study
Caffeine decreases intermittent hypoxia in preterm infants nearing term-equivalent age.
To determine whether intermittent hypoxia (IH) persisting after 36 weeks postmenstrual age (PMA) can be attenuated using caffeine doses sufficient to maintain caffeine concentrations >20 μg ml-1. ⋯ Caffeine doses of 14 to 20 mg kg-1 day-1 were sufficient to maintain caffeine concentrations >20 μg ml-1 and reduce IH in preterm infants at 36 to 38 weeks PMA.