Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
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Several positions are currently utilized for operating patients with posterior fossa lesions. Each individual position has its own risks and benefits, and none has demonstrated its superiority. A dreaded, and probably underreported, complication of these procedures is cervical cord infarction with quadriplegia. ⋯ With this report, we want to draw the attention of neurosurgeons to the possibility of the occurrence of this dreadful complication during posterior fossa procedures. Retrospectively, the only measures that might have helped to avoid this complication in our patient would have been using the prone position and intraoperative monitoring of evoked potentials.
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The aim of this study was to investigate the possible beneficial effects of mycophenolate mofetil in comparison with methylprednisolone in an experimental model of spinal cord injury in young rats. ⋯ Our results showed that the administration of mycophenolate mofetil on traumatic spinal cord injury decreases apoptosis and improves neurologic recovery.