Journal of hepatology
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Journal of hepatology · Nov 2012
Comparative StudyRegular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery.
The aim of this study was to determine the influence of coffee and other caffeinated drinks on liver fibrosis of severely obese European patients. ⋯ Consumption of regular coffee but not espresso is an independent protective factor for liver fibrosis in severely obese European patients.
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Journal of hepatology · Nov 2012
Comparative StudyRecurrence of hepatocellular cancer after liver transplantation: the role of primary resection and salvage transplantation in East and West.
Greater tumor aggressiveness and different management modalities of hepatocellular cancer (HCC) before liver transplantation (LT) may explain the higher recurrence rates reported in Asia. This study investigates the prognostic factors for HCC recurrence in a Western and an Eastern HCC patient cohort in order to analyze the respective roles of tumor- and management-related factors on the incidence of post-LT HCC recurrence. ⋯ LR followed by salvage "for HCC recurrence" LT represents the main reason for a higher HCC recurrence rate in the Hong Kong patients, but not LR followed by salvage "for liver failure" LT in the Roman group. This approach towards HCC before LT may not be universally applicable. The precise patient background must be taken into account in order to identify the best pre-LT strategy.