Computer methods and programs in biomedicine
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Comput Methods Programs Biomed · Nov 2011
Increased variation of the response index of nociception during noxious stimulation in patients during general anaesthesia.
Analgesia is an important part of general anaesthesia, but no direct indicators of nociceptive-anti-nociceptive balance have been validated in detail. The Response Index of Nociception (RN) is a multiparameter approach which combines photoplethysmographic waveform (PPG), State Entropy (SE), Response Entropy (RE), and heart rate variability (HRV). We aimed at evaluating RN during general anaesthesia; especially we wanted to compare pre- and post-index values of certain noxious stimuli to the average index values. Our assumption was that RN could be a useful indicator of nociceptive-anti-nociceptive balance during the surgery. ⋯ Changes in RN can be used to detect noxious stimuli during surgery. RN also predicted movement in our patients under propofol-remifentanil anaesthesia.