The Clinical journal of pain
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Randomized Controlled Trial Clinical Trial
Efficacy of a self-management group intervention for elderly persons with chronic pain.
To assess the efficacy of a self-management group intervention in improving physical functioning, mood, and pain among elderly persons with chronic pain, and to identify factors that may be associated with improvement. ⋯ This study provides preliminary support for the efficacy of a self-management group intervention for older adults with chronic pain and has implications for future studies of such approaches for this and similar populations.
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Randomized Controlled Trial Clinical Trial
Acupuncture during labor can reduce the use of meperidine: a controlled clinical study.
To evaluate the effectiveness of acupuncture as an analgesic during labor. ⋯ Acupuncture during labor reduced the requirement for other painkillers and has high patient satisfaction in this randomized, unblinded, controlled study.
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Analgesic drug development as currently undertaken is limited by a number of factors that contribute to the paucity of new analgesics introduced into clinical practice despite marked advances in delineating of the molecular-genetic mechanisms contributing to acute and chronic pain. The participants in this workshop explored the unmet need in analgesia and recommended strategies for enhancing analgesic drug development in the future. The workshop concluded that translating scientific advances into improved pain relief will require new thinking and a cooperative effort among the pharmaceutical industry, regulatory agencies, funding agencies, the biomedical research community, professional societies and clinicians. The workshop also recommended that a better understanding of the epidemiology of pain could contribute to improvement in clinical trial methodology and outcome measures.
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Randomized Controlled Trial Clinical Trial
The cholecystokinin antagonist proglumide enhances the analgesic effect of dihydrocodeine.
To investigate the potential pro-analgesic effect of the non-specific CCK antagonist proglumide on the analgesia produced by dihydrocodeine. ⋯ The CCK antagonist proglumide enhances the analgesic effect of dihydrocodeine.
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The treatment of pain during pregnancy other than that of labor is a clinical issue that has not been addressed in a systematic manner. ⋯ Experience in women seeking recovery from opioids and their newborns illustrates that opioids are an effective and safe pharmacological option for the treatment of pain during pregnancy. Controlled studies are needed to expand knowledge in this clinical area.