Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
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Comparative Study Clinical Trial Controlled Clinical Trial
Total-body irradiation before bone marrow transplantation for acute leukemia in first or second complete remission. Results and prognostic factors in 326 consecutive patients.
In order to assess the influence of total-body irradiation (TBI) on the outcome and incidence of complication after bone marrow transplantation (BMT), we retrospectively analyzed our patients treated for acute leukemia and conditioned with TBI prior to BMT. ⋯ The outcome of BMT patients conditioned with TBI for acute leukemia was not significantly influenced by the TBI technique, and TRM seemed to be lower in patients treated after 1985. On the other hand, cataract incidence was significantly influenced by the instantaneous dose rate.
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Comparative Study
[The observation of edema in the substantia alba during postoperative brain irradiation. The role of computed tomographic studies].
The aim of our study was to determine on CT whether a relation exists between a radiation-induced brain edema, treated with diuretics and its corresponding Houndsfield Units (HU). ⋯ Measurements of HU can serve as a good indicator for spontaneous or diuretic induced changes of a white matter edema during radiation therapy.
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Randomized Controlled Trial Comparative Study Clinical Trial
[Prospective study on the prevention of heterotopic ossification after total hip replacement. Non-steroidal anti-inflammatory agents versus radiation therapy].
Two prospective trials were undertaken to assess the comparative efficacy of early postoperative irradiation with different radiation doses versus the postoperative use of nonsteroidal antiinflammatory drugs (NSAID) for prevention of heterotopic ossification (HO) following prothetic total hip replacement (THP). ⋯ Prophylactic irradiation of the operative site after hip replacement is more effective than the use of NSAID. Because no significant difference between the fractionated ingle dose irradiation was found and the latter is more comfortable for patients and more economical, irradiation with single 7 Gy fraction should be preferred.
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Case Reports Comparative Study
[Lung cancer--hopelessness in inoperability? A 10-year follow-up].
According to reports of Durrant et al. [19] and Berry et al. [5] it was concluded that non-operable non-small cell lung tumors cannot be cured. In this consequence initiation of radiotherapy was fixed at the beginning of symptoms. However, long-time survivors in our follow-up lead us to analyse not only quality of life and secondary therapeutic effects but also this special group with the results of the whole collective treated in the same period of interest. ⋯ The reported treatment results in a period with modest technological possibilities, a telecobalt unit, should encourage to a curative intention, when dissemination cannot be proved. If lung cancer is limited to the primary region with or without lymph node metastases the possibility of tumor elimination is small but feasible. If inoperable lung cancer is not curable, this mostly is not due to inability of locoregional radiotherapy, but rather can be seen as a lack of reliable and permanent elimination or prevention of