Journal of pain and symptom management
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J Pain Symptom Manage · Mar 2025
Review Meta AnalysisSymptoms of Hematologic Tumors Patients after CAR-T Therapy: a Systematic Review and Meta-Analysis.
Patients with hematologic neoplasms after Chimeric antigen receptor T-cell (CAR-T) therapy have multiple syndromes, with corresponding symptoms. ⋯ Patients with hematologic neoplasms treated by CAR-T suffer from multiple symptoms, including depression, fatigue, and so on. Instruments used to evaluate symptoms and the evaluating time may influence the outcome of symptom assessment.
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J Pain Symptom Manage · Feb 2025
Review Meta AnalysisNon-pharmacological therapies for depression in women with breast cancer at different treatment phases: A systematic review and network meta-analysis.
Various non-pharmacological therapies (NPTs) have been found to be helpful for depression in women with breast cancer (BC). However, the relative efficacy of different NPTs in women with BC during different treatment phases is unclear. ⋯ Our study confirmed the efficacy of several NPTs for depression in women with BC during inter-/post-treatment phases. These results should inform future clinical decisions and guidelines for depression in women with BC.
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J Pain Symptom Manage · Jan 2025
Review Meta AnalysisEfficacy and Safety of Pregabalin and Gabapentin for Pruritus: A systematic review and meta-analysis.
Limited data existed on the efficacy and safety of novel antiepileptic drugs (pregabalin and gabapentin) in treating pruritus. ⋯ The novel antiepileptic drugs pregabalin and gabapentin demonstrated significant therapeutic value in the treatment of pruritus, with a favorable safety profile. Compared to commonly used pruritus treatments such as antihistamines and antidepressants, these medications offered a promising alternative.
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J Pain Symptom Manage · Jan 2025
Review Meta AnalysisEffects of Exercise in Adults With Cancer Pain: A Systematic Review and Network Meta-Analysis.
Pain is one of the most common symptoms of cancer patients, affecting the patient's physical, psychological, behavioral, social relations and other aspects. Previous studies have demonstrated that exercise is effective for cancer pain, and the optimal exercise is still unknown. ⋯ Current evidence shows that CEP is the best way to relieve the pain intensity of cancer patients, and mind-body exercise is the best way to reduce pain interference of cancer patients. Due to the limited number and quality of the included studies, the above conclusions need to be further verified by more high-quality studies.
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J Pain Symptom Manage · Dec 2024
Review Meta AnalysisEffects of aromatherapy on quality of life and pain in patients with cancer: A meta-analysis.
Cancer has become a chronic disease to which new therapeutic approaches are being applied and many patients are interested in the long-term consequences of these approaches. Aromatherapy is one approach that has been used as a safe and comfortable method to alleviate symptoms in patients with cancer, and its effects on various aspects of life have been reported. ⋯ The findings indicate statistically significant improvements in QoL when combining aromatherapy and massage, but it was not possible to disentangle the individual effects of each. Considering the characteristics of cancer patients, aromatherapy has beneficial effects as a non-pharmacological method. Further research is needed to investigate the effect of aromatherapy on symptom management, considering factors such as the duration of cancer development and type of cancer.