Journal of thoracic imaging
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Review
CT evaluation of diffuse infiltrative lung disease: dose considerations and optimal technique.
This review provides a comprehensive outline of radiation issues in the high-resolution computed tomography (HRCT) scans obtained for the diagnosis and follow-up of diffuse lung disease. Specifically, the evidence indicating risk from the radiation at the level used in HRCT, recommended dose levels for HRCT, radiation dose reduction strategies, and suggested protocols are discussed.
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Collagen vascular disease is one of the most common causes of chronic infiltrative lung disease. Patterns of lung injury from collagen vascular disease include nonspecific interstitial pneumonia (NSIP), usual interstitial pneumonia, organizing pneumonia, bronchiectasis, obliterative bronchiolitis, and pulmonary arterial hypertension. The prevalence of each entity varies according to the specific disease entity. ⋯ In polymyositis, a combination of organizing pneumonia and NSIP is characteristic. Sjögren syndrome is characterized by bronchiectasis and lymphoid interstitial pneumonia, often associated with thin-walled cysts. Ankylosing spondylitis is associated with upper lobe fibrosis, and may be complicated by mycetoma.