The Laryngoscope
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Using a retrospective approach, the aim of this study was to confirm the previously described value of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG-PET/CT) in patients with primary extranodal lymphoma of the head and neck region. Additionally, the clinical significance of the semiquantitative analysis of the standardized uptake value (SUV), its predictive role in the follow-up setting, and its value in detection of synchronous primaries were studied. ⋯ (18)F-FDG-PET/CT imaging is a potent primary staging tool. It also has application as an instrument for evaluation of follow-up and response to therapy in patients suffering from primary extranodal lymphoma and for detection of secondary malignancies. Furthermore, (18)F-FDG uptake by the primary lesion may be related to better survival.
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In clinical research, which is distinctly quantitative and rigidly fixed to a written protocol, the need for precision is great, especially when multicenter trials are planned. The Sunnybrook Facial Grading System (SB) is a well-established tool for assessing facial movement outcomes; however, some ambiguities do arise. The purpose of this study was to construct specific grading criteria and to test the intra-rater and inter-rater reliability before and after the use of these criteria. The hypothesis was that even in naïve observers, specific criteria improve reliability. ⋯ To our knowledge, this is the first report of specific criteria for completing the SB system. It is also the first in-depth description of the location within the system in which the majority of variances occur.