Metabolic brain disease
The most recent articles from: April 2015
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Metabolic brain disease · Apr 2015
ReviewIntracerebral hemorrhage in mouse models: therapeutic interventions and functional recovery.
There has been strong pre-clinical research on mechanisms of initial cell death and tissue injury in intracerebral hemorrhage (ICH). This data has led to the evaluation of several therapeutics for neuroprotection or the mitigation of early tissue damage. ⋯ This review examines the testing of candidate therapeutics in mouse models of ICH for their effect on tissue protection and repair. This review will help the readers compare it to the extensively researched rat model of ICH and thus enhance work that are pending in mouse model.