Journal of critical care
-
Journal of critical care · Oct 2017
Experience using high-dose glucose-insulin-potassium (GIK) in critically ill patients.
To audit the use of GIK in terms of safety, haemodynamic effects, and impact on catecholamine dosage. ⋯ High-dose GIK can be safely used in critically ill patients, though blood glucose and potassium levels must be monitored frequently. GIK was associated with improved CI and blood lactate levels. Impact on survival requires prospective evaluation.
-
Journal of critical care · Oct 2017
Observational StudyPrevalence and clinical significance of early high Endotoxin Activity in septic shock: An observational study.
To measure the prevalence of elevated Endotoxin Activity (EA) in a large cohort of patients with Septic Shock (SS), and to assess its value as an early indicator of Gram-Negative (GN) infection, disease severity, and patient risk. ⋯ Early after SS onset, patients showed a high prevalence of endotoxemia, particularly those infected with GN bacteria. The EA assay might be a useful marker of disease severity. The complexity of such patients, however, limits EA accuracy in identifying GN sepsis and predicting outcome.