Journal of critical care
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Journal of critical care · Feb 2018
Multicenter StudyUntreated hypertension as predictor of in-hospital mortality in intracerebral hemorrhage: A multi-center study.
Hypertension is a significant risk factor for intracerebral hemorrhage (ICH). The importance of managing blood pressure to reduce the risk of ICH has been recognized. However, few studies have focused on ICH outcomes due to untreated hypertension. ⋯ Subjects with untreated-hypertension were younger and had fewer comorbidities when compared with treated-hypertension and were similar when compared to normotensive individuals. Once demographic and in-hospital factors were accounted for, untreated-hypertension subjects demonstrated significantly increased in-hospital mortality following ICH when compared with normotensive individuals.
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Journal of critical care · Feb 2018
Multicenter Study Observational StudyAssociation between strained capacity and mortality among patients admitted to intensive care: A path-analysis modeling strategy.
To evaluate the associations between strained ICU capacity and patient outcomes. ⋯ Strained capacity was associated with increased ICU mortality, partly mediated through greater illness acuity. Future work should consider both the direct and indirect relationships of strain on outcomes.
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Journal of critical care · Dec 2017
Multicenter Study Observational StudyClinical predictors of early death from sepsis.
Patients with severe sepsis who experience rapid, early deterioration and death are of particular concern. Our objective was to identify predictors of early death in Emergency Department (ED) patients with severe sepsis. ⋯ Initial serum lactate and mSOFA score were independent predictors of mortality within 24h of ED admission in patients with severe sepsis.
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Journal of critical care · Dec 2017
Multicenter Study Observational StudyDelirium and exposure to psychoactive medications in critically ill adults: A multi-centre observational study.
Investigate the relationship between psychoactive drugs and delirium. ⋯ The identification of psychoactive drugs as modifiable delirium risk factors plays an important role in the management of critically ill patients. This is particularly important given the burden of exposure and combinations of drugs used in this vulnerable patient population.
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Journal of critical care · Dec 2017
Multicenter StudyA multifactor model for predicting mortality in critically ill patients: A multicenter prospective cohort study.
The objective of this study was to develop a model using a combination of routine clinical variables to predict mortality in critically ill patients. ⋯ The developed multifactor model can be used to effectively predict mortality in critically ill patients at ICU admission.