Journal of critical care
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Journal of critical care · Apr 2023
Identifying high-risk phenotypes and associated harms of delayed time-to-antibiotics in patients with ICU onset sepsis: A retrospective cohort study.
To identify phenotypes of Intensive Care Unit (ICU) onset sepsis and its associated harms of delayed time-to-antibiotics. ⋯ Septic patients with respiratory or cardiovascular dysfunction were associated with harms of delayed time-to-antibiotics.
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Journal of critical care · Apr 2023
Right ventricular echocardiographic parameters and prediction of stroke volume in ischemic cardiogenic shock: A retrospective study.
This study investigated which commonly used right ventricular (RV) echocardiographic parameter correlates best with stroke volume (SV) estimated by Doppler echocardiography in ischemic cardiogenic shock (CS). ⋯ RVOT VTI correlated better (albeit weakly) to and best predicted SV compared to TAPSE, RV S', and TR Vmax in patients admitted to intensive care with CS. This study suggests that RVOT VTI has the potential as a therapeutic target to optimize SV in CS.
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Journal of critical care · Apr 2023
Letter Observational StudyCoagulopathy correlates with muscle titin injury in critically ill patients.
We hypothesized that coagulopathy independently contributes to muscle injury focusing to titin fragmentation, and investigated their correlations. ⋯ Coagulopathy correlated with muscle titin fragmentation, as an independent risk factor.
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Journal of critical care · Apr 2023
Alactic base excess is an independent predictor of death in sepsis: A propensity score analysis.
Alactic base excess (ABE) is a novel biomarker defined as the sum of lactate and standard base excess and estimates the renal capability of handling acid-base disturbances in sepsis. The objective of this study is to see if ABE is an independent predictor of mortality in septic patients with and without renal dysfunction. ⋯ Negative ABE is an independent predictor of in-hospital mortality in septic patients with and without renal dysfunction.