Journal of Korean medical science
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J. Korean Med. Sci. · Oct 2019
Case ReportsThe First Case of Para-Bombay Blood Type Encountered in a Korean Tertiary Hospital.
Para-Bombay phenotypes are rare blood groups that have inherent defects in producing H antigens associated with FUT1 and/or FUT2. We report the first case of para-Bombay blood type in a Southeast Asian patient admitted at a tertiary hospital in Korea. A 23-year-old Indonesian man presented to the hospital with fever and was diagnosed with a disseminated nontuberculous mycobacterium infection and anemia. ⋯ Ala110Thr, rs56342683, FUT1*01W.02), and a synonymous variant, c.390C>T (p. Asn130=, rs281377, Se357), respectively. This highlights the need for both forward and reverse grouping.
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J. Korean Med. Sci. · Sep 2019
Increased Carotid Intima-Media Thickness (IMT) in Hyperuricemic Individuals May Be Explained by Hyperhomocysteinemia Associated with Renal Dysfunction: a Cross-Sectional Study.
Both hyperuricemia and hyperhomocysteinemia are known as main risk factors of cardiovascular diseases. There has been, however, no report on the relationship between carotid intima-media thickness (IMT) and homocysteine (Hcy) in hyperuricemic patients. This study aimed to investigate how hyperuricemia is associated with increased carotid IMT with a focus on hyperhomocysteinemia. ⋯ These results suggest that renal function impairment in hyperuricemic patients may worsen carotid IMT by increasing serum Hcy levels.