Acta radiologica
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Longitudinal metabolic changes of total choline (tCho), creatine+phosphocreatine (total creatine, tCr), and N-acetylaspartate (NAA) in the pregenual anterior cingulate cortex (pACC) of patients with major depressive disorder (MDD) have not been well evaluated. ⋯ A progressive decrease in the NAA/tCr ratio in the pACC of patients with MDD was demonstrated and the decrease in this ratio was at the highest rate in the early period after illness onset. These findings indicate the neuronal degeneration and dysfunction of the pACC, and the importance of early clinical intervention in female patients with MDD.
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Comparative Study
Diffusion-weighted MRI of metastatic liver lesions: is there a difference between hypervascular and hypovascular metastases?
Different perfusion characteristics and histopathologic features of liver metastasis may potentially lead to different diffusion-weighted magnetic resonance imaging (DW-MRI) characteristics which can affect the performance of DW-MRI in their diagnosis. ⋯ Liver metastases are not a homogenous group of lesions with uniform DW-MRI features. Hypervascular metastases demonstrate significantly lower ADC values compared to hypovascular metastases. DW-MRI improved detection of hypervascular metastases compared to T2-w images alone and is a useful adjunct to T2-w images for their detection.
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Comparative Study
Effect of surgery on periventricular white matter in normal pressure hydrocephalus patients: comparison of two methods of DTI analysis.
Diffusion tensor imaging (DTI) is a useful tool for assessing changes that occur in microstructures. We have developed a novel method for region of interest (ROI) delineation in the assessment of DTI parameters in patients with normal pressure hydrocephalus (NPH). ⋯ Our results show that use of a novel method of DTI data analysis may be more sensitive to local changes induced by surgical procedures. Furthermore, this novel method was able to detect the transmantle pressure gradient related to the regional stress distribution.