Acta radiologica
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Randomized Controlled Trial Comparative Study
Comparison of three software systems for semi-automatic volumetry of pulmonary nodules on baseline and follow-up CT examinations.
Early diagnosis of lung cancer in a treatable stage is the main purpose of lung cancer screening by computed tomography (CT). Accurate three-dimensional size and growth measurements are essential to assess the risk of malignancy. Nodule volumes can be calculated by using semi-automated volumetric software. Systematic differences in volume measurements between packages could influence nodule categorization and management decisions. ⋯ Software packages for lung nodule evaluation yield significant differences in volumetric measurements and VDT. This variation affects the classification of lung nodules, especially in follow-up examinations.
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Randomized Controlled Trial Comparative Study
Single dose ivabradine versus intravenous metoprolol for heart rate reduction before coronary computed tomography angiography (CCTA) in patients receiving long-term calcium channel-blocker therapy.
In patients with contraindication for beta-blockers who are also under long-term calcium channel-blocker therapy for any reason, ivabradine may be used as an alternative treatment to achieve the target heart rate. ⋯ Single dose ivabradine is safe and significantly more effective than i.v. metoprolol in decreasing HR in patients under calcium channel-blocker therapy.