Hematology/oncology clinics of North America
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The elucidation of factors involved in the development of Wilms tumor represents a remarkable and fruitful marriage between epidemiology, clinical practice, histopathology, and molecular biology. Many fascinating research problems remain to be solved, and it is to be expected that the study of Wilms tumor will continue to yield valuable insights, not only in relation to Wilms tumor itself but also into tissue development and processes involved in malignant transformation in general.