Hematology/oncology clinics of North America
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Hematol. Oncol. Clin. North Am. · Dec 2009
ReviewChronic immune thrombocytopenia in children: epidemiology and clinical presentation.
Immune thrombocytopenic purpura (ITP) is one of the most common acquired bleeding disorders in children. Most children with ITP will have acute disease, self-limited thrombocytopenia that resolves completely within weeks or months, with or without therapy. ⋯ Treatment for these children is an ongoing clinical challenge, as few therapies offer long-term remission, and all have significant side effects and toxicities. This article focuses on the management of clinically significant chronic ITP in the pediatric population.