Archives of gynecology and obstetrics
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Arch. Gynecol. Obstet. · Jun 2011
Are maternal and fetal parameters related to perinatal mortality in HELLP syndrome?
We designed this retrospective study to evaluate the association between maternal and fetal parameters and perinatal mortality in hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome. ⋯ Maternal laboratory and clinical parameters were not associated with fetal mortality. Fetal prematurity, low birth weight, and low Apgar scores were significantly associated with fetal mortality. The HELLP syndrome and severe preeclampsia may be life threatening to the mother; therefore, the accepted treatment is expeditious delivery. Our study indicates that prevention of prematurity must be the main priority for the fetus in pregnancies complicated by the HELLP syndrome. This can be efficaciously achieved using glucocorticoid therapy for lung maturity and ensuring that delivery is at an experienced hospital with a multidisciplinary approach including a neonatal intensive care unit.
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Arch. Gynecol. Obstet. · May 2011
Neural networks prediction of preterm delivery with first trimester bleeding.
This paper illustrates a retrospective study of the outcome of those pregnancies that continued from an initial episode of bleeding in first trimester. ⋯ The success rate of prediction obtained using the feed forward backpropogation network is 70%. Hence, this model can be used to identify women at the risk of premature delivery for planning antenatal care and clinical interventions in pregnancy.
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Arch. Gynecol. Obstet. · May 2011
Randomized Controlled Trial Comparative StudyRectal versus oral misoprostol for active management of third stage of labor: a randomized controlled trial.
To test that rectal misoprostol is effective for active management of third stage of labor, and probably with less side effects than oral misoprostol. ⋯ Rectal misoprostol is effective in the management of third stage of labor, and with a significant decrease in side effects. Lesser dose and other routes could be explored in the future.
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Arch. Gynecol. Obstet. · May 2011
Randomized Controlled TrialUmbilical cord blood acid-base and gas analysis after early versus delayed cord clamping in neonates at term.
To compare umbilical cord acid-base status and blood gas analysis between umbilical cords clamped within 10 s and at 2 min of delivery. ⋯ A delay of 2 min before umbilical cord clamping does not significantly change acid-base and gas analysis results, with the exception of a higher mean umbilical artery pO(2) value in the delayed clamping group.
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Arch. Gynecol. Obstet. · May 2011
Comparative StudyImpact of positron emission tomography/computed tomography in the management of patients with epithelial ovarian carcinoma after treatment.
The aims of this study were to compare the usefulness and reliability of integrated whole-body positron emission tomography/computed tomography (PET/CT) using (18)F-fluorodeoxyglucose (FDG) with those of contrast-enhanced multidetector CT during regular follow-up in patients after initial treatment of ovarian cancer, to assess the impact of FDG-PET/CT on the confirmation of recurrence, restaging, and clinical management of patients, and to determine the incremental information provided by PET/CT. ⋯ Both integrated FDG-PET/CT and contrast-enhanced multidetector CT are sensitive surveillance modalities for the detection of recurrent ovarian cancer; the use of both modalities aids decisions on treatment plans and may ultimately have a favorable impact on prognosis. However, contrast-enhanced multidetector CT is recommended for the regular follow-up for ovarian cancer patients after initial treatment.