Infectious disease clinics of North America
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Infect. Dis. Clin. North Am. · Sep 2020
ReviewInfective Endocarditis in Persons Who Use Drugs: Epidemiology, Current Management, and Emerging Treatments.
Infective endocarditis associated with injection drug use (IDU-IE) is markedly increasing in the United States and Canada. Long-term outcomes are dismal and stem from insufficient substance use disorder treatment. ⋯ We discuss approaches to opioid use disorder care and harm reduction in the inpatient setting and review opportunities to address preventable infections among persons injecting drugs. We highlight barriers to implementing optimal treatment and consider novel approaches that may reshape infective endocarditis associated with injection drug use treatment in coming years.