Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
The effect of d-tubocurarine priming on an ED95 dose of vecuronium bromide.
To examine how priming with ED10 d-tubocurarine prior to the administration of ED95 vecuronium bromide affects onset and duration of neuromuscular blockade. ⋯ These results indicate that crossover dosing of nondepolarizing muscle relaxants may have synergistic effects. Priming with ED10 d-tubocurarine prior to an ED95 dose of vecuronium shortens the time to 80% T1 depression and produces satisfactory intubating conditions at 90 seconds, without prolonging the duration of the Therefore, d-tubocurarine is an attractive drug for priming vecuronium in short operative procedures that require muscle relaxation.
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Randomized Controlled Trial Clinical Trial
Intravenous ketorolac as an adjuvant to pediatric patient-controlled analgesia with morphine.
To assess the effects of a single intraoperative dose of intravenous (i.v.) ketorolac on postoperative opioid dose requirements, quality of analgesia as assessed by the patient, and frequency of opioid-related side effects during pediatric patient-controlled analgesia (PCA) with morphine. ⋯ A single intraoperative dose of i.v. ketorolac appears to be opioid dose sharing, to provide superior analgesia, and to decrease the frequency of urinary retention during the first 12 hours of postoperative pediatric PCA with morphine.
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Randomized Controlled Trial Clinical Trial
Anesthetic-postoperative morphine regimens for cesarean section and postoperative oxygen saturation monitored by a telemetric pulse oximetry network for 24 continuous hours.
To document the effects of compromised respiratory function on oxygen saturation (SpO2) after cesarean section via the telemetric pulse oximetry network (TPON) for 24 continuous hours. ⋯ All 3 regimens risked low SpO2, with the EA/EM regimen having the highest risk but the best analgesia. Neither general nor epidural anesthesia combined with postoperative parenteral morphine influenced SpO2 postoperatively. In this study, the TPON provided a feasible method of detecting hypoxemia early on in the general ward setting.
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Uvular necrosis as a potential source of infection is a poorly detected complication that should be considered as part of the differential diagnosis of postoperative sore throat. We report a unique case of uvular necrosis following endotracheal intubation. The patient complained of a severe sore throat and foreign body sensation 48 hours following surgery.