Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
The efficacy of guanfacine in reducing perioperative hemodynamic changes and volatile anesthetic requirement.
To evaluate the efficacy of guanfacine, an alpha 2-adrenergic agonist, for attenuating hemodynamic changes associated with tracheal intubation or extubation, providing intraoperative hemodynamic stability, and reducing inhalation anesthetic requirement in patients undergoing gynecologic surgery. ⋯ Guanfacine 1 mg administered orally proved to be an effective premedicant for providing intraoperative hemodynamic stability, attenuating the increase in BP and HR associated with tracheal intubation and extubation, and reducing anesthetic requirements without increasing the incidence of perioperative complications.
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Randomized Controlled Trial Comparative Study Clinical Trial
Does monitoring end-tidal isoflurane concentration improve titration during general anesthesia?
To assess the value of end-tidal anesthetic gas monitoring with respect to intraoperative hemodynamic stability and recovery times. ⋯ This study suggests that end-tidal isoflurane monitoring does not improve the titration of isoflurane during general anesthesia.
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Clinical Trial Controlled Clinical Trial
Efficient inspired concentration of sevoflurane for vital capacity rapid inhalation induction (VCRII) technique.
To evaluate the efficient inspired concentration of sevoflurane for a vital capacity rapid inhalation induction (VCRII) technique with respect to induction time, characteristics, and acceptability. ⋯ Sevoflurane 6% can be recommended for VCRII, but increasing the concentration higher than this does not markedly shorten the induction time and thus seems to add little benefit.
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Randomized Controlled Trial Clinical Trial
The effect of cricoid pressure application on airway patency.
To assess the incidence of upper airway obstruction associated with the application of cricoid pressure (Sellick's maneuver) by experienced anesthetists. ⋯ The use of manual cricoid pressure, even by experienced anesthetists, causes a degree of airway obstruction and can cause complete airway occlusion.
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To ascertain the benefits of the preoperative discussion of the risks of anesthesia with parents of ASA status I or II pediatric day surgery patients. ⋯ Our study suggests the benefits of the explanation of the risks of anesthesia appear to be rooted in satisfying parental responsibility and understanding, and not in providing information for decision making or anxiety relief. Anesthesiologists should not feed compelled to always detail all the risks, but should seek to satisfy individual parental needs.