Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
A mixture of mivacurium and rocuronium is comparable in clinical onset to succinylcholine.
To compare the clinical onset and duration of a combination of mivacurium and rocuronium with succinylcholine, and to determine the efficacy of this mixture for rapid tracheal intubation. ⋯ This combination of mivacurium and rocuronium is comparable to succinylcholine in both clinical onset time and quality of intubating conditions. When rapid onset of dense neuromuscular blockade and intermediate clinical duration is desirable, this mixture may be an acceptable alternative to succinylcholine.
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Randomized Controlled Trial Clinical Trial
Propofol at conscious sedation doses produces mild analgesia to cold pressor-induced pain in healthy volunteers.
To determine whether subanesthetic doses of propofol have analgesic effects in healthy volunteers. ⋯ Our laboratory results are consistent with the commonly accepted clinical practice of supplementing propofol with an opioid in conscious sedation procedures to provide a satisfactory level of pain relief.
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Randomized Controlled Trial Comparative Study Clinical Trial
Parental presence plus oral midazolam decreases frequency of 5% halothane inductions in children.
To determine the frequency of 5% halothane induction and behavioral distress during inhalation induction with both oral midazolam and parental presence compared with parental presence alone. ⋯ The combination of parental presence plus oral midazolam reduces the likelihood of needing a 5% rapid halothane induction when compared with parental presence without premedication.