Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
An alternative method to alleviate postoperative nausea and vomiting in children.
To evaluate whether isopropyl alcohol vapor is an effective treatment for postoperative nausea and vomiting. ⋯ Under the conditions of this study, repetitive inhaled isopropyl alcohol only achieved a transient antiemetic effect in children with established postoperative nausea or vomiting following general anesthesia and surgery.
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Clinical Trial Controlled Clinical Trial
Pain relief in children following outpatient surgery.
To evaluate perioperative analgesia, prescription patterns, pain relief, and parental care of children undergoing outpatient surgery. ⋯ Despite a wide range of surgical procedures being performed on children on an ambulatory basis, current selection of patients for outpatient surgery is appropriate given the ability of the parents to manage their children's pain and to care for their children at home.
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Randomized Controlled Trial Clinical Trial
Comparative effects of oral clonidine and intravenous esmolol in attenuating the hemodynamic response to epinephrine injection.
To evaluate oral clonidine and intravenous esmolol in blunting hemodynamic changes associated with intranasal injection of an epinephrine-containing local anesthetic solution during general anesthesia. ⋯ In this healthy, young, nonsmoking outpatient population, premedication with oral clonidine, 0.2 to 0.4 mg, was effective in blunting the acute hemodynamic changes associated with injection of an epinephrine-containing local anesthetic solution during endoscopic sinus or septoplasty surgery.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Comparison of renal function following anesthesia with low-flow sevoflurane and isoflurane.
To evaluate postoperative renal function after patients were administered sevoflurane under conditions designed to generate high concentrations of compound A. ⋯ There were no statistically significant differences in the renal effects of sevoflurane or isoflurane in surgical patients undergoing low-flow anesthesia for up to 8 hours. Low-flow sevoflurane anesthesia under clinical conditions expected to produce high levels of compound A appears as safe as low-flow isoflurane anesthesia.
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Randomized Controlled Trial Clinical Trial
A comparison of the onset and clinical duration of high doses of cisatracurium and rocuronium.
To determine the onset and clinical duration of cisatracurium and rocuronium in equipotent doses in balanced opioid/isoflurane anesthesia. ⋯ With equipotent intubating doses of rocuronium and cisatracurium, rocuronium produces a more rapid onset of muscle relaxation. The data suggest a tendency toward more rapid clinical recovery of cisatracurium compared to equipotent doses of rocuronium, although these differences were not statistically significant.