Journal of clinical anesthesia
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Randomized Controlled Trial Multicenter Study Comparative Study
Effect of endovenous lidocaine on analgesia and serum cytokines: double-blinded and randomized trial.
This trial aimed to compare postoperative analgesia, opioid consumption, duration of ileus and hospital stay, and cytokine levels in patients undergoing laparoscopic cholecystectomies who received intravenous lidocaine in comparison with a control group. ⋯ Intravenous lidocaine was not able to reduce postoperative pain, opioid consumption, and duration of ileus or length of hospital stay. However, its anti-inflammatory effect was noticeable.
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Randomized Controlled Trial Multicenter Study Observational Study
A multicenter study of the analgesic effects of epidural chloroprocaine after lower limb orthopedic surgery.
To investigate the effects and optimal concentration of chloroprocaine for epidural analgesia after lower limb orthopedic surgery. ⋯ Epidural 1.2% chloroprocaine with 0.4μg/mL fentanyl could generate proper analgesic effects with little influence on mobility in patients undergoing lower limb orthopedic surgery. In addition, it could generate a good sense and movement separation, facilitating the early functional training.
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Multicenter Study Comparative Study
Variability in anesthesiologists' approach to the preoperative management of asthmatic children.
No consensus guidelines exist for the preoperative treatment of asthmatic children referred for elective surgery. We investigated the attitude of pediatric anesthesiologists to this issue. ⋯ A wide variability exists in pediatric anesthesiologists' approach to the preoperative management of asthmatic children for most common case scenarios. This is probably explained by the heterogeneity of asthma, the type of surgery, the lack of guidelines, and the paucity of data. Similarities as well as differences exist between pediatric anesthesiologists and pulmonologists. Further studies and implementation of consensus guidelines are needed.