Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
Hydroxyethyl starch (HES) does not directly affect renal function in patients with no prior renal impairment.
To examine the effects of hydroxyethyl starch (HES) on renal function. ⋯ Hydroxyethyl starch administration appears to be risk-free with regard to renal function in patients without preexisting renal dysfunction who undergo general anesthesia. The relevance of the decrease in aldosterone following HES therapy needs further investigation.
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Randomized Controlled Trial Comparative Study Clinical Trial
Nicardipine versus nitroprusside for breakthrough hypertension following carotid endarterectomy.
To evaluate the effectiveness of nicardipine and nitroprusside for breakthrough hypertension following carotid endarterectomy. ⋯ Nicardipine administration produced more rapid BP control, most likely related to the administration of a loading dose. In addition to more rapid control, nicardipine-treated patients had less variability in BP and required significantly fewer additional interventions. Although no patient suffered a major event during this study, this study was not powered sufficiently to assess safety.
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To evaluate the relationship between sedative therapy and self-extubation in a large medical-surgical intensive care unit (ICU). ⋯ In intubated ICU patients, benzodiazepines may not consistently treat agitation effectively or prevent self-extubation. Such an effect may be due to paradoxical excitation, disorientation during long-term administration, or differences in drug administration between ICU and operating room (OR) environments.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of no airway device, the Guedel-type airway and the Cuffed Oropharyngeal Airway with mask ventilation during manual in-line stabilization.
To compare two different types of oropharyngeal airway: the Guedel-type oral airway and the Cuffed Oropharyngeal Airway (COPA), with respect to the effectiveness of positive-pressure ventilation (PPV) through a face mask in patients with in-line stabilization of the head and neck. ⋯ Although clinical differences often appear trivial, the COPA is more effective on mask ventilation than the Guedel-type airway when used in patients with manual in-line stabilization.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of wire reinforced tubes with warmed standard tubes to facilitate fiberoptic intubation.
To compare the ease of insertion of a warmed standard tracheal tube to that of a wire reinforced tracheal tube when placed over a flexible fiberoptic bronchoscope. ⋯ When performing elective flexible fiberoptic bronchoscopy for intubation, we recommend using the less expensive warmed standard tracheal tube.