Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Remifentanil versus propofol as adjuncts to regional anesthesia. Remifentanil 3010 Study Group.
To compare the safety and efficacy of remifentanil and propofol as adjuncts to regional anesthesia in patients undergoing orthopedic or urogenital surgery. ⋯ At the doses studied, remifentanil was more effective than propofol in minimizing pain without producing excessive sedation. Remifentanil was associated with more transient respiratory depression and short-term nausea. Our findings indicate that the initial remifentanil rate should be 0.1 microg/kg/min (50% lower than the study's initial rate) and should be further decreased an additional 50% in the elderly to minimize adverse effects.
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Randomized Controlled Trial Comparative Study Clinical Trial
High concentration versus incremental induction of anesthesia with sevoflurane in children: a comparison of induction times, vital signs, and complications.
To compare sevoflurane induction times and complications in children during a high concentration, primed-circuit method and an incremental induction technique. ⋯ In healthy pediatric patients undergoing mask induction of general anesthesia with sevoflurane, the induction time can be significantly shortened without an increase in the frequency of airway or vital sign complications using a high concentration, primed circuit technique compared with a conventional, incremental induction method.
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Randomized Controlled Trial Comparative Study Clinical Trial
Droperidol-ondansetron combination versus droperidol alone for postoperative control of emesis after total abdominal hysterectomy.
To investigate the hypothesis that the combination of ondansetron and droperidol would be more effective than droperidol alone in reducing nausea and vomiting. ⋯ For patients undergoing total abdominal hysterectomies, the addition of ondansetron to droperidol increases the time until first rescue and reduces the number of emetic episodes, as well as the percentage of patients, having at least one emetic episode.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparative effects of Ringer's acetate and lactate solutions on intraoperative central and peripheral temperatures.
To compare the effects of Ringer's lactate (LR) and Ringer's acetate (AR) solutions on core body and peripheral temperatures during isoflurane or sevoflurane anesthesia. ⋯ There was no significant difference between AR and LR in the preservation of heat during either sevoflurane or isoflurane anesthesia. However, AR may be superior to LR for maintaining central temperature during the early period of isoflurane anesthesia.
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Randomized Controlled Trial Comparative Study Clinical Trial
Pharmacy savings generated by preoperative administration of clonidine.
To evaluate the effects of the preoperative administration of clonidine by the oral, intramuscular (i.m.), or epidural routes, on isoflurane expense during total abdominal hysterectomy. ⋯ In the patient population studied, premedication with 300 microg oral, i.m., or epidural clonidine, similarly and significantly reduced the expense of isoflurane during general anesthesia of an approximate duration of two hours. However, the cost of the epidural kit offsets the savings in isoflurane.