Journal of clinical anesthesia
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Randomized Controlled Trial Multicenter Study Clinical Trial
Etomidate and thiopental-based anesthetic induction: comparisons between different titrated levels of electrophysiologic cortical depression and response to laryngoscopy.
To determine whether etomidate-based induction can provide better hemodynamics than a standard thiopental sodium-based anesthetic induction. ⋯ Etomidate-based anesthetic induction, titrated to EEG burst suppression, produced stable hemodynamics during laryngoscopy and intubation as compared with lower dose, more "classic" inductions with etomidate or thiopental.
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Randomized Controlled Trial Comparative Study Clinical Trial
Removal of the laryngeal mask airway in children: deep anesthesia versus awake.
To compare the incidence of adverse airway events identified with removal of the laryngeal mask airway (LMA) from an awake child or from a child before his or her airway reflexes had returned. ⋯ Removal of the LMA during anesthesia and after return of airway reflexes results in a similar incidence of airway problems in children.
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Randomized Controlled Trial Comparative Study Clinical Trial
Postoperative analgesia using a low-dose, oral-transdermal clonidine combination: lack of clinical efficacy.
To determine if a lower than previously reported oral-transdermal clonidine regimen could reduce postoperative morphine requirements without producing systemic side effects. ⋯ The low-dose oral-transdermal clonidine regimen evaluated failed to reduce postoperative morphine requirements, although patients who received clonidine were still at risk for developing hypotension.
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Randomized Controlled Trial Comparative Study Clinical Trial
Laryngo-pharyngeal complaints following laryngeal mask airway and endotracheal intubation.
To investigate the incidence and severity of laryngo-pharyngeal complaints following anesthesia with the use of a laryngeal mask airway (LMA) compared with endotracheal intubation in adults. ⋯ There is a distinct pattern of laryngo-pharyngeal complaints following the use of the LMA and endotracheal intubation. With regard to minor laryngo-pharyngeal morbidity, the advantage of the LMA to endotracheal intubation is questionable.
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Comparative Study Clinical Trial
Comparative recovery of 50-Hz and 100-Hz posttetanic twitch following profound neuromuscular block.
To determine if posttetanic twitch following 100-Hz tetanic stimulation enables titration of a nondepolarizing relaxant infusion to a greater depth of block than that achieved with posttetanic twitch following 50 Hz. ⋯ Posttetanic twitch following 100-Hz tetanic stimulation enables titration of a vecuronium infusion to a greater depth of block than posttetanic twitch following 50-Hz tetanic stimulation. The present findings should enable more effective titration of this relaxant, thereby reducing the likelihood of unwanted patient movement or unduly prolonged recovery due to relaxant overdosing.