Journal of clinical anesthesia
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Comparative Study
Secondary polycythemia does not increase the risk of perioperative hemorrhagic or thrombotic complications.
To determine the effects of secondary polycythemia on perioperative hemorrhagic and thrombotic complications. ⋯ Secondary polycythemia does not impart any added perioperative risk.
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Comparative Study
Pharmacokinetics and effects of 9-amino-1,2,3,4-tetrahydroacridine in the immediate postoperative period in neurosurgical patients.
To determine the effects of intravenous (IV) 9-amino-1,2,3,4-tetrahydroacridine (THA) on postoperative somnolence in comparison to its pharmacokinetics. ⋯ The duration of the effects of THA as an antagonist of postoperative sedation was only about double that seen previously after the IV administration of physostigmine in a similar group of patients, although the elimination half-life of THA was six times longer than that of physostigmine. A larger dose of THA possibly could have been given to prolong the period of antagonism of sedation, but the profile of adverse effects seen even at the doses used precluded that option.
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Randomized Controlled Trial Clinical Trial
Continuous alfentanil infusion in pediatric patients undergoing general anesthesia for complete oral restoration.
To study the safety and efficacy of continuous alfentanil infusions in children. ⋯ Alfentanil appears to be a safe anesthetic. The reason for prolonged discharge time in the alfentanil-anesthetized patient is unclear, but it may be related to postoperative vomiting.
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Clinical Trial
Accelerated recovery from doxacurium-induced neuromuscular blockade in patients receiving chronic anticonvulsant therapy.
To determine whether a drug interaction exists between doxacurium and anticonvulsants. ⋯ Chronic treatment with anticonvulsants results in more rapid recovery from neuromuscular blockade produced by doxacurium.