Journal of clinical anesthesia
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Hemodynamics and emergence profile of remifentanil versus fentanyl prospectively compared in a large population of surgical patients.
To compare the responses to, and hemodynamics associated with surgical stress, recovery profiles, and anesthesiologists' satisfaction following balanced general anesthesia using either remifentanil or fentanyl in a large-scale population. ⋯ This study confirms previous observations on the hemodynamic properties associated with remifentanil and extends these to a wider context than previously reported. These characteristics provide clinicians with an alternative in opioid-based anesthesia.
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Randomized Controlled Trial Comparative Study Clinical Trial
A comparison of propofol and remifentanil for sedation and limitation of movement during periretrobulbar block.
To compare clinical conditions in patients sedated with propofol or remifentanil during combined peri-bulbar and retrobulbar block (PRBB) for cataract surgery. ⋯ Respiratory depression with remifentanil was mild and not clinically significant. Remifentanil sedation for this application was superior to sedation with propofol.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparing the efficacy of prophylactic metoclopramide, ondansetron, and placebo in cesarean section patients given epidural anesthesia.
To compare the relative efficacy of prophylactic metoclopramide, ondansetron, and placebo in nonemergent cesarean section patients given epidural anesthesia intraoperatively and for the first 24-hour period after delivery. ⋯ In cesarean section patients given epidural anesthesia, prophylactic ondansetron, 4 mg IV, is more efficacious and has a higher patient satisfaction than that with metoclopramide, 10 mg IV, or placebo in preventing nausea and achieving complete responses during intraoperative period and the first 24-hour postdelivery period. However, there is no difference between ondansetron and metoclopramide in reducing frequency of vomiting. Prophylactic ondansetron 4 mg IV is more effective in preventing nausea than vomiting.
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Randomized Controlled Trial Clinical Trial
Absorption of lidocaine during aspiration anesthesia of the airway.
To determine the optimal solution to use when anesthetizing the airway by aspiration of lidocaine. ⋯ This technique produced anesthesia of the airway to the carina, safely, suitable for awake intubation, in 94 of 95 patients. The use of 1% lidocaine, 0.2 to 0.3 mL. kg(-1), so that the volume is 10 to 20 mL, is recommended.
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Randomized Controlled Trial Clinical Trial
Structured preoperative patient education for patient-controlled analgesia.
To investigate the effectiveness of a structured preoperative education program in patients receiving patient-controlled analgesia (PCA). ⋯ Structured preoperative PCA education did not affect patient outcome. The early improvement in patient satisfaction was minimized by continued education and pain team supervision during the rest of the postoperative period.