Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
A double-blind, randomized comparison of low-dose rocuronium and atracurium in a desflurane anesthetic.
To compare the neuromuscular and hemodynamic effects of rocuronium and atracurium when administered during a desflurane-based anesthetic. ⋯ Rocuronium at a dose of 0.45 mg/kg possesses a fairly rapid onset of neuromuscular blockade and has short:intermediate duration of action when used with a desflurane anesthetic. This quality makes it a desirable drug for operations of relatively short duration. Rocuronium at a dose of 0.45 mg/kg has a faster onset and shorter duration than atracurium, at 0.5 mg/kg, when used with a desflurane anesthetic.
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Randomized Controlled Trial Comparative Study Clinical Trial
Commercial propofol solutions: is the more expensive also the more effective?
To compare the efficacy and safety of four commercial propofol solutions marketed in Israel. ⋯ Diprivan, Recofol, Diprofol, and Propofol Abbott are equally effective as anesthesia induction drugs for dilation and curettage, with a similar incidence of adverse effects. Because cost limitations have become a significant factor in medical care, the choice of drug in this group should be based solely on cost considerations.
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Randomized Controlled Trial Clinical Trial
Evaluation of the safety and efficacy of epidural ketamine combined with morphine for postoperative analgesia after major upper abdominal surgery.
To evaluate the efficacy of the combination of epidural ketamine and morphine compared with epidural morphine alone for postoperative pain relief following major upper abdominal surgery. ⋯ The addition of epidural ketamine 1 mg/kg to morphine 50 microg/kg improved analgesia after major upper abdominal surgery without increasing side effects.
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Clinical Trial
Influence of pneumoperitoneum and patient positioning on respiratory system compliance.
To investigate the influence of pneumoperitoneum (PP) and posture on respiratory compliance and ventilation pressures. ⋯ Creation of PP at an IAP of 15 mmHg reduced respiratory system compliance, and increased peak inspiratory and mean airway pressures, which quickly returned to normal values after deflation. Head-down or head-up position did not further alter those parameters.