Pediatric radiology
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Pediatric radiology · Jul 2002
Clinical TrialMRI-based blood oxygen saturation measurements in infants and children with congenital heart disease.
Vessel oxygen saturation can be determined with MR oximetry using an in vivo measurement of signal decay (T2) and the calibration curve relating T2 to blood oxygen saturation (%HbO(2)), where: 1/T2=1/T2O+K (1-%HbO(2)/100)(2) and K is a constant parameter which correlates with measured fibrinogen levels. The ability to noninvasively measure %HbO(2) in cardiac chambers and vessels has enormous potential in children with congenital heart disease (CHD). ⋯ Adult values for T2-%HbO(2) calibration can be used to measure blood oxygen saturation in vivo in children with CHD.