Journal of anesthesia
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Journal of anesthesia · Dec 2018
Randomized Controlled Trial Multicenter StudyThe effect of anesthetic technique on µ-opioid receptor expression and immune cell infiltration in breast cancer.
Clinical histological studies demonstrate that the distribution of natural killer (NK) cells, other immune cells and μ-opioid receptors (MOR) within cancer tissue can predict cancer prognosis. No clinical study has evaluated whether anesthetic technique influences immune cell and MOR expression within human breast cancer. ⋯ General anesthesia with opioid analgesia increased resected tumor MOR expression compared with propofol-paravertebral anesthetic technique, but the anesthetic technique did not significantly influence the expression of immune cell markers.
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Journal of anesthesia · Dec 2018
Randomized Controlled Trial Comparative StudyUltrasound-guided quadratus lumborum block in pediatrics: trans-muscular versus intra-muscular approach.
Quadratus lumborum (QL) block has four approaches. However, there is difference between the four approaches regarding efficacy, safety and adverse effects. The primary objective of this study is to compare the analgesic effect between trans-muscular and intra-muscular approaches of the QL block in pediatric patients for elective lower abdominal surgery. ⋯ TQL is better than IQL in the analgesic efficacy following the pediatric lower laparotomy.
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Journal of anesthesia · Dec 2018
Angiotensin II-mediated suppression of synaptic proteins in mouse hippocampal neuronal HT22 cell was inhibited by propofol: role of calcium signaling pathway.
Angiotensin II (Ang II) has been shown to be involved in neurological disorders. Propofol demonstrated neuroprotective effects in neurons. ⋯ Ang II, via AT1 receptor, induced oxidative stress and reduced the expression of synapsin I and PSD95 in HT22 cells. Propofol may increase synapsin I and PSD95 expression by inhibiting oxidative stress and stimulating calcium signaling pathway.
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Journal of anesthesia · Dec 2018
Comment LetterReply to the letter regarding NADPH oxidase inhibitor.
Abstract
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Journal of anesthesia · Dec 2018
Randomized Controlled TrialImpact of non-invasive continuous blood pressure monitoring on maternal hypotension during cesarean delivery: a randomized-controlled study.
This study aimed to investigate the efficacy of the ClearSight™ system (Edwards Lifesciences, Irvine, CA) for reducing the incidence of hypotension compared with the traditional oscillometric blood pressure monitoring in cesarean delivery under spinal anesthesia. ⋯ The accuracy and trending ability of the ClearSight™ system for blood pressure measurement was clinically acceptable in cesarean delivery under spinal anesthesia, leading to reductions in maternal hypotension and nausea.