Journal of anesthesia
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Journal of anesthesia · Dec 2018
Suppressed descending pain modulatory and enhanced sensorimotor networks in patients with chronic low back pain.
Although cerebral structural and functional changes were uncovered by neuroimaging in patients with chronic low back pain (CLBP), their associations remain to be clarified. We co-analyzed anatomical and functional magnetic resonance imaging data in those patients and tested whether cortical gray matter volume changes are associated with altered pain modulatory networks underlying chronification of pain. ⋯ Patients showed a decreased volume of cortical center for descending pain modulation and an increased volume of sensorimotor network, in association with suppressed descending pain modulatory and cerebellum-limbic networks and enhanced sensorimotor network during pain. Such structural and functional alterations might be part of cerebral pathophysiology of CLBP.
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Journal of anesthesia · Dec 2018
Comment LetterReply to the letter regarding NADPH oxidase inhibitor.
Abstract
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Journal of anesthesia · Dec 2018
Randomized Controlled Trial Multicenter StudyThe effect of anesthetic technique on µ-opioid receptor expression and immune cell infiltration in breast cancer.
Clinical histological studies demonstrate that the distribution of natural killer (NK) cells, other immune cells and μ-opioid receptors (MOR) within cancer tissue can predict cancer prognosis. No clinical study has evaluated whether anesthetic technique influences immune cell and MOR expression within human breast cancer. ⋯ General anesthesia with opioid analgesia increased resected tumor MOR expression compared with propofol-paravertebral anesthetic technique, but the anesthetic technique did not significantly influence the expression of immune cell markers.
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Journal of anesthesia · Dec 2018
Randomized Controlled Trial Comparative StudyUltrasound-guided quadratus lumborum block in pediatrics: trans-muscular versus intra-muscular approach.
Quadratus lumborum (QL) block has four approaches. However, there is difference between the four approaches regarding efficacy, safety and adverse effects. The primary objective of this study is to compare the analgesic effect between trans-muscular and intra-muscular approaches of the QL block in pediatric patients for elective lower abdominal surgery. ⋯ TQL is better than IQL in the analgesic efficacy following the pediatric lower laparotomy.
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Journal of anesthesia · Dec 2018
Randomized Controlled TrialImpact of non-invasive continuous blood pressure monitoring on maternal hypotension during cesarean delivery: a randomized-controlled study.
This study aimed to investigate the efficacy of the ClearSight™ system (Edwards Lifesciences, Irvine, CA) for reducing the incidence of hypotension compared with the traditional oscillometric blood pressure monitoring in cesarean delivery under spinal anesthesia. ⋯ The accuracy and trending ability of the ClearSight™ system for blood pressure measurement was clinically acceptable in cesarean delivery under spinal anesthesia, leading to reductions in maternal hypotension and nausea.