Clinical imaging
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Comparative Study
Diffusion-weighted MRI with parallel imaging technique: apparent diffusion coefficient determination in normal kidneys and in nonmalignant renal diseases.
The purpose of the study was to assess the capability and the reliability of apparent diffusion coefficient (ADC) measurements in the evaluation of different benign renal abnormalities. Twenty-five healthy volunteers and 31 patients, divided into seven different groups (A-G) according to pathology, underwent diffusion-weighted magnetic resonance imaging (DW MRI) of the kidneys using 1.5-T system. DW images were obtained in the axial plane with a spin-echo echo planar imaging single-shot sequence with three b values (0, 300, and 600 s/mm²). ⋯ An important difference was also observed among Group D (hydronephrosis=4.82±0.35×10⁻³ mm² s⁻¹) and Groups A, B, and C (P<.05), whereas no differences were found between Groups B and C (P>.05). A considerable correlation between glomerular filtration rate and ADC was found (P=.04). In conclusion, significant differences were detected among different patient groups, and this suggests that ADC measurements can be useful in differentiating normal renal parenchyma from most commonly encountered nonmalignant renal lesions.
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Case Reports
Non-Hodgkin's lymphoma of the bone and the liver without lymphadenopathy revealed on FDG-PET/CT.
Primary extranodal lymphomas are much less frequent than nodal lymphomas. Osseous and hepatic lymphomas commonly present with additional nodal lesions. ⋯ We describe a case of extranodal non-Hodgkin's lymphoma with numerous osseous and hepatic lesions without any lymph node involvement on FDG-PET/CT images. This is the first report of the coexistence of both osseous and hepatic lymphoma in the same patient without any lymph node involvement.