Clinical imaging
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MRI brain segmentation and volume estimation of gray matter (GM), white matter (WM) and cerebrospinal fluid (CSF) are important for many neurological applications. Signal intensity based measurements, such as the current statistical parametric mapping (SPM) based volume estimation techniques rely on T1W images that involve a series of pre-processing steps, making it impractical for clinical use. ⋯ Brain imaging in children using SyMRI can identify and calculate estimates of GM, WM, CSF volumes. With our work, we have shown high similarity of volume estimates in GM and WM using SyMRI with a systematic bias for CSF values. The ease of use of this software can make this quantitative data to be used clinically along with the routine anatomical images.