Journal of nephrology
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Journal of nephrology · Jul 2013
Microalbuminuria can predict the development of acute kidney injury in critically ill septic patients.
Microalbuminuria (MA) has long been associated with development of chronic kidney diseases in diabetic or hypertensive patients. However, its value in predicting acute kidney injury (AKI) in an intensive care unit (ICU) setting has never been reported. This study aimed to investigate the link between MA and AKI. ⋯ ACR obtained on entry to ICU was highly predictive of AKI, and was also associated with mortality rate and ICU length of stay.
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Journal of nephrology · Mar 2013
Comparative StudyStent-grafts versus angioplasty and/or bare metal stents for failing arteriovenous grafts: a cross-over longitudinal study.
A well-established method to preserve failing synthetic arteriovenous grafts (AVGs) dialysis accesses is percutaneous transluminal angioplasty (PTA). Nevertheless, the one-year primary patency rate following PTA is approximately 25%. This study was designed to compare the angiographic and clinical outcomes following stent-graft insertion versus angioplasty and/or bare metal stenting (BMS) of recurrently failing AVGs, because of anastomotic and/or venous outflow stenoses. ⋯ Stent-graft placement significantly improves primary patency of anastomotic and venous outflow stenoses in recurrently failing prosthetic arteriovenous grafts.
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Journal of nephrology · Mar 2013
Quantification of experimental acute kidney injury by computer-assisted imaging of lectin phytohemagglutinin E.
Acute kidney injury (AKI) in sepsis accompanied by functional impairment regularly lacks histologic pathology to a similar extent. Moderately reproducible - semi-quantitative - scoring systems still remain the method of choice to quantify the extent of experimental AKI. Our aim was to establish a rather simple, fast, and reproducible staining protocol to quantify loss of brush border (BB) in septic AKI. ⋯ Our results demonstrate that PHA-E lectin staining followed by planimetric quantification is a reliable tool to analyze loss of BB during experimental AKI.
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Journal of nephrology · Jan 2013
Randomized Controlled TrialIgA nephropathy with severe chronic renal failure: a randomized controlled trial of corticosteroids and azathioprine.
Therapeutic nihilism is common in IgA nephropathy (IgAN) and renal insufficiency. ⋯ Six-year renal survival was similar in the 2 groups. At Cox analysis the addition of azathioprine may be slightly more effective than corticosteroids alone in patients with chronic renal insufficiency, although with an increase of side effects.