Acta neurologica Scandinavica
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Acta Neurol. Scand. · Feb 2011
Evaluation of fatigue in Parkinson's disease using the Brazilian version of Parkinson's Fatigue Scale.
Fatigue is common in Parkinson's disease (PD). However, factors associated with fatigue in PD are still controversial. This study aimed to translate the Parkinson's Fatigue Scale (PFS) into Brazilian-Portuguese, to test its psychometric properties, and to assess the severity of fatigue in PD as well as its relation to demographic and clinical features, depression, anxiety, excessive daytime sleepiness and cognitive performance. ⋯ Fatigue is a common non-motor symptom in PD and seems to be associated with female gender, dysthymia, severity of depression and daily somnolence.
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Acta Neurol. Scand. · Feb 2011
Efficacy and safety of intravenous lacosamide in refractory nonconvulsive status epilepticus.
Lacosamide (LCM) is a novel antiepileptic drug (AED) recently approved as an adjunctive therapy in the treatment of partial seizures in adults. LCM is available in oral and intravenous formulations, has linear pharmacokinetics and a unique mechanism of action. ⋯ Intravenous LCM may be safe and efficacious as an add-on AED for the treatment of NCSE when standard therapy fails.