Acta neurologica Scandinavica
-
Acta Neurol. Scand. · Jul 2013
Randomized Controlled Trial Comparative StudyAmitriptyline vs divalproate in migraine prophylaxis: a randomized controlled trial.
This study compares efficacy and safety of divalproate extended release (DVA-ER) and amitriptyline (AMT) in migraine. ⋯ Divalproate extended release is more effective at 3 months than AMT; however, at 6 months, both are equally effective in migraine prophylaxis.
-
Hospital admission in otherwise healthy patients following a first unprovoked seizure is controversial. We aimed to evaluate the influence of admission in a neurology department on the identification of risk factors for seizure recurrence in patients with a first unprovoked seizure. ⋯ Risk factors for seizure recurrence were detected during admission in nearly a quarter of the patients who presented to the emergency room with a first unprovoked seizure. Because the main advantage of admission is the EEG recording, we suggest that an early EEG should be obtained in these patients either during admission or through a special accelerated outpatient arrangement.