Acta neurologica Scandinavica
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Acta Neurol. Scand. · Jun 2014
Multicenter Study Clinical TrialEfficacy and tolerability of add-on lacosamide in children with Lennox-Gastaut syndrome.
Available data on the efficacy of lacosamide in children with Lennox-Gastaut syndrome (LGS) are scarce and controversial. We present our experience with lacosamide therapy in children affected by LGS. ⋯ A third of children with LGS were responders after lacosamide adjunctive therapy. Although caution is still necessary when the drug is used in children with LGS, our preliminary observations suggest that lacosamide might be effective and represent a possible therapeutic option in children affected by LGS.