Acta neurologica Scandinavica
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Acta Neurol. Scand. · Nov 2020
Randomized Controlled Trial Multicenter StudyClinical outcomes and safety profile of Tenecteplase in wake-up stroke.
Tenecteplase has probably pharmacological and clinical advantages in the treatment of acute ischemic stroke. There are lacking data about safety and efficacy of tenecteplase in wake-up stroke (WUPS). ⋯ In WUPS patients treated in NOR-TEST, there was no difference in clinical outcomes at 90 days and no ICH events or deaths were observed in either alteplase- or tenecteplase-treated patients. Clinical Trial Registration-URL: https://www.clinicaltrials.gov. Unique identifier: NCT01949948.