Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
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Comparative Study
Bone measures in HIV-1 infected children and adolescents: disparity between quantitative computed tomography and dual-energy X-ray absorptiometry measurements.
Investigators have found that dual-energy X-ray absorptiometry (DXA) of areal bone mineral density (BMD) values in HIV-1 infected children and adolescents are reduced. Volumetric bone density (BD) measured by quantitative computed tomography (CT) in this population has not been studied. This study was designed to evaluate bone measurements in HIV-1 infected children and adolescents using DXA and CT. ⋯ HIV-1 infected children and adolescents have lower vertebral and whole body BMC and BMD DXA measures. In contrast, vertebral BD measurements by CT are normal. The lower bone measurements were primarily due to the decreased bone and body size of the HIV-1 subjects.