Acta obstetricia et gynecologica Scandinavica
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Acta Obstet Gynecol Scand · Jan 2009
The novel ischemia marker 'ischemia-modified albumin' is increased in normal pregnancies.
The aim of this prospective case-control study was to determine the change in serum maternal ischemia-modified albumin (IMA) during normal pregnancies. A total of 117 pregnant (first trimester (n=24), second trimester (n=34), and third trimester (n=35)) and non-pregnant healthy women (n=23) were included. Maternal serum IMA, Malondialdehyde (MDA), and albumin levels were measured. ⋯ Furthermore, a significant negative correlation between serum IMA and albumin levels (r=-0.354, p<0.001) was found, and there was a weak positive correlation between serum albumin and MDA levels (r=0.334, p<0.001). Serum IMA, which has recently been developed as a clinical marker of ongoing myocardial ischemia, appears to be elevated in normal pregnancy. This may be due to the physiologic oxidative stress state of pregnancy.
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Acta Obstet Gynecol Scand · Jan 2009
Women's fear of childbirth and preference for cesarean section--a cross-sectional study at various stages of pregnancy in Sweden.
To investigate Swedish women's level of antenatal fear of childbirth at various gestational ages, and factors associated with intense fear and with preference for cesarean section. ⋯ When a woman requests a cesarean section, both primary fear of birth and traumatic childbirth experiences need to be considered and dealt with. The W-DEQ can be used at any time during pregnancy in order to identify pregnant women who suffer from intense fear of childbirth.
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Acta Obstet Gynecol Scand · Jan 2009
Lumbopelvic pain associated with catastrophizing and fear-avoidance beliefs in early pregnancy.
To examine and compare levels of catastrophizing, fear-avoidance beliefs, physical ability, and health-related quality of life in women with and without lumbopelvic pain (LP and NLP) in early pregnancy. ⋯ It is important to consider exaggerated negative thoughts about pain experiences and fear-avoidance beliefs when treating women with LP during pregnancy and to be aware of the great impact lumbopelvic pain has on women's lives during early pregnancy.
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Acta Obstet Gynecol Scand · Jan 2009
Review Meta AnalysisSystematic review of progesterone for the prevention of preterm birth in singleton pregnancies.
A Cochrane review in 2006 concluded that further knowledge is required before recommendation can be made with regard to progesterone in the prevention of preterm birth. ⋯ In women with a singleton pregnancy and previous preterm delivery, progesterone reduces the rates of preterm delivery before 32 weeks, perinatal death, as well as respiratory distress syndrome and necrotizing enterocolitis in the newborn. Women with a short cervix or preterm labor may also benefit from progesterone, but further evidence is needed to support such a recommendation. Follow-up studies should focus on possible metabolic complications in the mother or the offspring.
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Acta Obstet Gynecol Scand · Jan 2009
Randomized Controlled TrialEfficacy and tolerability of oral bovine lactoferrin compared to ferrous sulfate in pregnant women with iron deficiency anemia: a prospective controlled randomized study.
To compare the effects of bovine lactoferrin with ferrous sulfate on iron nutritional status and to evaluate their tolerability in 100 pregnant women with iron deficiency anemia. ⋯ The results show that bovine lactoferrin has the same efficacy as ferrous sulfate in restoring iron deposits with significantly fewer gastrointestinal side effects.