Acta cirúrgica brasileira
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Acta cirúrgica brasileira · May 2009
The influence of lidocaine and racemic bupivacaine on neuromuscular blockade produced by rocuronium. A study in rat phrenic nerve-diaphragm preparation.
To evaluate in vitro lidocaine and racemic bupivacaine effects in neuromuscular transmission and in neuromuscular blockade produced by rocuronium. ⋯ Local anesthetics potentiated the blockade caused by rocuronium. The alterations of MEPP identify presynaptic action.
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Acta cirúrgica brasileira · May 2009
Preconditioning abolishion by midazolam in isolated hearts of rats.
To study the effects of benzodiazepine midazolam in the coronary flow (Cflo), cardiac frequency (CF) and myocardial contractility in isolated hearts of rats subjected to ischemic preconditioning (IPC). ⋯ Midazolam, when administered before the ischemia, was unable to prevent the ischemic deterioration of the myocardium. When administered before the preconditioning, it has abolished its protective effect.