Acta cirúrgica brasileira
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Acta cirúrgica brasileira · Jul 2015
Skin microcirculatory changes reflect early the circulatory deterioration in a fulminant sepsis model in the pig.
In the pathophysiology of sepsis tissue perfusion dysfunction is a crucial driving force. Thus the early recognition is highly important. Concerning the early hours of bacteremia, and the systemic inflammatory response reaction leading to sepsis we aimed to investigate the micro- and macrocirculatory changes. ⋯ During bacteremia and the early phase of sepsis microcirculatory impairment can be detected soon, even hours before the deterioration in hemodynamic parameters in this porcine model.