Acta psychiatrica Scandinavica
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Acta Psychiatr Scand · Aug 2015
Review Meta Analysis Comparative StudyThe prevalence and predictors of type two diabetes mellitus in people with schizophrenia: a systematic review and comparative meta-analysis.
To conduct a meta-analysis investigating the prevalence of type two diabetes mellitus (T2DM) in people with schizophrenia compared to controls. ⋯ People with schizophrenia are at least double the risk of developing T2DM according to recognized T2DM criteria. Proactive lifestyle and screening programmes should be given clinical priority.
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Acta Psychiatr Scand · Jun 2015
Randomized Controlled TrialMaintained superiority of chronotherapeutics vs. exercise in a 20-week randomized follow-up trial in major depression.
To investigate the long-term antidepressant effect of a chronotherapeutic intervention. ⋯ In this clinical study patients continued to improve in the follow-up phase and obtained very high remission rates. This is the first study to show adjunct short-term wake therapy and long-term bright light therapy as an effective and feasible method to attain and maintain remission.
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Acta Psychiatr Scand · May 2015
Randomized Controlled TrialCommunity treatment orders: clinical and social outcomes, and a subgroup analysis from the OCTET RCT.
Despite widespread use internationally, there is no convincing evidence that community treatment orders (CTO) (legal regimes making out-patient treatment compulsory), reduce readmission rates or have wider patient benefit. The primary and secondary outcomes of the Oxford Community Treatment Order Evaluation Trial (OCTET) (hospitalisation) showed no benefit. This article will, first, test the effect of community compulsion on wider clinical and social outcomes and on patients' experiences of services and the use of treatment pressure and second, explore differential effects in different groups of patients. ⋯ CTOs do not have benefit on any of the tested outcomes, or for any subgroup of patients. Their continued use should be carefully reconsidered.
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Acta Psychiatr Scand · Apr 2015
Randomized Controlled Trial Multicenter StudyNeurocognitive impairment in a large sample of homeless adults with mental illness.
This study examines neurocognitive functioning in a large, well-characterized sample of homeless adults with mental illness and assesses demographic and clinical factors associated with neurocognitive performance. ⋯ Homeless adults with mental illness experience impairment in multiple neuropsychological domains. Much of the variance in our sample's cognitive performance remains unexplained, highlighting the need for further research in the mechanisms underlying cognitive impairment in this population.