Journal of magnetic resonance imaging : JMRI
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To evaluate the feasibility and reproducibility of quantitative cartilage imaging with parallel imaging at 3T and to determine the impact of the acceleration factor (AF) on morphological and relaxation measurements. ⋯ The study demonstrated that parallel imaging can be applied to current knee cartilage quantification at AF = 2 without degrading measurement accuracy with good reproducibility while effectively reducing scan time. Shorter imaging times can be achieved with higher AF at the cost of SNR.
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J Magn Reson Imaging · Oct 2007
Optimization and validation of a fully-integrated pulse sequence for modified look-locker inversion-recovery (MOLLI) T1 mapping of the heart.
To optimize and validate a fully-integrated version of modified Look-Locker inversion-recovery (MOLLI) for clinical single-breathhold cardiac T1 mapping. ⋯ We present an optimized implementation of MOLLI for fast T1 mapping with high spatial resolution, which can be integrated into routine imaging protocols. T1 accuracy is superior to the original set of pulse sequence parameters and heart rate dependency is avoided.
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J Magn Reson Imaging · Oct 2007
Comparison of region-of-interest analysis with three different histogram analysis methods in the determination of perfusion metrics in patients with brain gliomas.
To compare routine ROI analysis and three different histogram analyses in the grading of glial neoplasms. The hypothesis is that histogram methods can provide a robust and objective technique for quantifying perfusion data in brain gliomas. Current region-of-interest (ROI)-based methods for the analysis of dynamic susceptibility contrast perfusion magnetic resonance imaging (DSC MRI) data are operator-dependent. ⋯ Histogram analysis of perfusion MR provides prediction of glioma grade, with peritumoral metrics outperforming tumoral and total tumoral metrics. Further refinement may lead to automated methods for perfusion data analysis.
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J Magn Reson Imaging · Oct 2007
Reconstruction of the human visual system based on DTI fiber tracking.
To apply and to evaluate the newly developed advanced fast marching algorithm (aFM) in vivo by reconstructing the human visual pathway, which is characterized by areas of extensive fiber crossing and branching, i.e., the optic chiasm and the lateral geniculate nucleus (LGN). ⋯ The present work shows that the advanced aFM, which is especially designed for overcoming tracking limitations within areas of extensive fiber crossing, handles the fiber crossing and branching within the optic chiasm and the LGN correctly, thus allowing the reconstruction of the entire human visual fiber pathway, from the intraorbital segment of the optic nerves to the visual cortex.
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To describe what, if any, specific long T(2)-related abnormalities occur in the white matter of subjects with either phenylketonuria (PKU) or multiple sclerosis (MS). ⋯ This study supports the usefulness of increasing the data acquisition window of the multiecho T(2) relaxation sequence to better characterize the T(2) decay from pathological brain.