Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Oct 2007
Reconstruction of the human visual system based on DTI fiber tracking.
To apply and to evaluate the newly developed advanced fast marching algorithm (aFM) in vivo by reconstructing the human visual pathway, which is characterized by areas of extensive fiber crossing and branching, i.e., the optic chiasm and the lateral geniculate nucleus (LGN). ⋯ The present work shows that the advanced aFM, which is especially designed for overcoming tracking limitations within areas of extensive fiber crossing, handles the fiber crossing and branching within the optic chiasm and the LGN correctly, thus allowing the reconstruction of the entire human visual fiber pathway, from the intraorbital segment of the optic nerves to the visual cortex.
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J Magn Reson Imaging · Oct 2007
High-resolution T1 mapping of the brain at 3T with driven equilibrium single pulse observation of T1 with high-speed incorporation of RF field inhomogeneities (DESPOT1-HIFI).
To investigate an alternative approach to correct for flip angle inaccuracies in the driven equilibrium single pulse observation of T1 (DESPOT1) T1 mapping method. ⋯ The described approach, dubbed DESPOT1-HIFI, permits whole-brain T1 mapping at 3T, with 1 mm(3) isotropic voxels, in a clinically feasible time (approximately 10 minutes) with T1 accuracy greater than 5% and with high precision.
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J Magn Reson Imaging · Oct 2007
Simultaneous myocardial and fat suppression in magnetic resonance myocardial delayed enhancement imaging.
To develop a method for fat suppression in myocardial delayed enhancement (MDE) studies that achieves effective signal intensity reduction in fat but does not perturb myocardial signal suppression. ⋯ The results indicate this modular-type approach optimizes fat suppression in myocardial delayed enhancement studies but does not perturb the basic IR pulse sequence or change basic acquisition parameters.
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J Magn Reson Imaging · Oct 2007
Quantification of rodent cerebral blood flow (CBF) in normal and high flow states using pulsed arterial spin labeling magnetic resonance imaging.
To implement a pulsed arterial spin labeling (ASL) technique in rats that accounts for cerebral blood flow (CBF) quantification errors due to arterial transit times (dt)-the time that tagged blood takes to reach the imaging slice-and outflow of the tag. ⋯ Even when flow is accelerated, CBF can be accurately determined using pulsed ASL, as long as dt and outflow of the tag are accounted for.